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Malaria Laboratory

Malaria Laboratory is conducting epidemiological studies in collaboration with national and international institutions to generate information on the dynamics and  transmission of Malaria in order to develop new alternatives that can be applied for the control and eventual elimination of this disease in the Amazon.

malaria


 

Organization

Laboratory Coordinator:

dioni  Dionicia Gamboa, Ph.D

Research Team:

  • Katherine Torres, PhD 
  • MSc. Elizabeth Villasis
  • MSc. Juan José Contreras
  • MSc. Pamela Rodríguez 
  • MSc. Carlos A. Fernandez Miñone
  • MSc. Jhonatan Alarcon 
  • Bsc. Beronica Infante
  • Katherine Garro
  • Yovanna Maldonado Espejo
  • Zenobia Choque Portilla
  • Rosa Alban 
  • Jeancarlo Feijoo Gamboa
  • Yulissa Vasquez Vergara

Collaboration and Funding

  • Belgian Agency for Development Cooperation, Bélgica.
  • Centers for Disease Control and Prevention (CDC), USA.
  • Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica (CONCYTEC), Perú.
  • Flemish Interuniversity Council for University Development Cooperation ( VLIR-UOS), Bélgica.
  • Fogarty International Center, National Institutes of Health (NIH), USA.
  • Fondos para la Innovación, Ciencia y Tecnología (FINCyT), Perú.
  • Foundation for Innovative New Diagnostics (FIND), Switzerland.
  • Institut Pasteur, Francia.
  • Institute of Tropical Medicine in Antwerp, Bélgica.
  • Instituto Nacional de Salud (INS), Perú.
  • Special Programme for Research and Training in Tropical Diseases (TDR), WHO, Switzerland.
  • Universidad Nacional de la Amazonía Peruana (UNAP), Perú.
  • University of Antwerp, Bélgica.
  • University of California - San Diego (UCSD), USA.


 

Recent Projects

  • Amazonia-ICEMR: International Centers of Excellence for Malaria Research. FINANCIAMIENTO: National Institutes of Health (NIH).
  • Amplificación isotérmica mediada por horquillas (LAMP) para buscar malaria asintomática y creación de un banco de muestras. FINANCIAMIENTO: Foundation for Innovative New Diagnostics (FIND).
  • Círculos de investigación: “Hacia la eliminación de la Malaria en el Perú”. FINAN- CIAMIENTO: CIENCIACTIVA-CONCYTEC.
  • Colección y preparación de muestras para el Control de Calidad de las Pruebas de Diagnóstico Rápido de malaria a partir de muestras clínicas con cepas nativas de Plasmodium vivax. FINANCIAMIENTO: Foundation for Innovative New Diagnostics (FIND).
  • Componente Malaria: Molecular tools development/validation for malaria diag- nostics and molecular surveillance in the Peruvian Amazon region (Act. 2.10), FA4. FINANCIAMIENTO: The Belgian Development Cooperation
  • Producción y evaluación de las proteínas PVMSP10, PVMSP7 y PVMSP8 de Plas- modium vivax y PFMSP10, PFRH2B de P. falciparum como nuevos marcadores de seroprevalencia en la Amazonía Peruana. FINANCIAMIENTO: FONDECYT.
  • Puntos calientes de malaria residual en el Perú y Brasil: estableciendo el marco para evaluar intervenciones mejoradas. FINANCIAMIENTO: Special Programme for Research and Training in Tropical Diseases WHO/TDR.
  • VLIR South Initiative: Joint project to strengthen research skills on molecular epidemiology and to uncover malaria transmission features relevant for its control in the Peruvian Amazon. FINANCIAMIENTO: VLIR-UOS.
  • VLIR-TEAM: Joint efforts for the Elimination of Malaria in the Peruvian Amazon. FINANCIAMIENTO: VLIR-UOS.


Relevant publications

  • Hupalo DN, Luo Z, Melnikov A, Sutton PL, Rogov P, Escalante A, et al. Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax. Nature Genetics. 2016;48(8):953–8.
  • Rosas-Aguirre A, Speybroeck N, Llanos-Cuentas A, Rosanas-Urgell A, Carrasco-Escobar G, Rodriguez H, et al. Hotspots of Malaria Transmission in the Peruvian Amazon: Rapid Assessment through a Parasitological and Serological Survey. Carvalho LH, editor. PLOS ONE. 2015;10(9):e0137458.
  • Pacheco MA, van Eijk AM, Barry AE, Gamboa D, Volkman SK, Escalante AA, et al. Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network. The American Journal of Tropical Medicine and Hygiene. 2015;93(3_Suppl):79–86.
  • Koepfli C, Rodrigues PT, Antao T, Orjuela-Sánchez P, Van den Eede P, Gamboa D, et al. Plasmodium vivax Diversity and Population Structure across Four Continents. Vinetz JM, editor. PLOS Neglected Tropical Diseases. 2015;9(6):e0003872.
  • Barbosa S, Gozze AB, Lima NF, Batista CL, Bastos M da S, Nicolete VC, et al. Epidemiology of Disappearing Plasmodium vivax Malaria: A Case Study in Rural Amazonia. Rodrigues MM, editor. PLoS Neglected Tropical Diseases. 2014;8(8):e3109.
  • Akinyi S, Hayden T, Gamboa D, Torres K, Bendezu J, Abdallah JF, et al. Multiple genetic origins of histidine-rich protein 2 gene deletion in Plasmodium falciparum parasites from Peru. Scientific Reports. 2013;3(1).
  • da Silva-Nunes M, Moreno M, Conn JE, Gamboa D, Abeles S, Vinetz JM, et al. Amazonian malaria: Asymptomatic human reservoirs, diagnostic challenges, environmentally driven changes in mosquito vector populations, and the mandate for sustainable control strategies. Acta Tropica. 2012;121(3):281–91.
  • Villasis E, Lopez-Perez M, Torres K, Gamboa D, Neyra V, Bendezu J, et al. Anti-Plasmodium falciparum invasion ligand antibodies in a low malaria transmission region, Loreto, Peru. Malaria Journal. 2012;11(1):361.
  • Moutinho P, Gil L, Cruz R, Ribolla P. Population dynamics, structure and behavior of Anopheles darlingi in a rural settlement in the Amazon rainforest of Acre, Brazil. Malaria Journal. 2011;10(1):174.
  • Gamboa D, Ho M-F, Bendezu J, Torres K, Chiodini PL, Barnwell JW, et al. A Large Proportion of P. falciparum Isolates in the Amazon Region of Peru Lack pfhrp2 and pfhrp3: Implications for Malaria Rapid Diagnostic Tests. Bjorkman A, editor. PLoS ONE. 2010;5(1):e8091.

 


Contact Information

 

Address: LID, laboratorio N° 309         

Av. Honorio Delgado 430

Urb. Ingeniería, San Martin de Porres. Lima - Perú.

 

Phone: +511 3190000 anexo 233317

 

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.